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Biologics R&D: select news
Selective STING Activation in Intratumoral Myeloid Cells via CCR2-Directed Antibody-Drug Conjugate TAK-500
https://pubmed.ncbi.nlm.nih.gov/39918395/
jeanfrancoismaison
May 31 min read
Macrophages suppress CD8 + T cell cytotoxic function in triple negative breast cancer via VISTA
https://pubmed.ncbi.nlm.nih.gov/40316725/
jeanfrancoismaison
May 31 min read
The main aspects of non-clinical studies required for obtaining marketing authorisation for small molecules and biologics/biopharmaceuticals in the European Union and the United States
https://pubmed.ncbi.nlm.nih.gov/40316008/
jeanfrancoismaison
May 31 min read
Application of new approach methodologies for nonclinical safety assessment of drug candidates
https://pubmed.ncbi.nlm.nih.gov/40316753/
jeanfrancoismaison
May 31 min read
Complicated pneumococcal pneumonia in the era of higher-valent pneumococcal conjugate vaccines: a systematic literature review and meta-analysis, 2001-2022
https://pubmed.ncbi.nlm.nih.gov/40314731/
jeanfrancoismaison
May 31 min read
Recent Advances in Immunotherapeutic and Vaccine-Based Approaches for the Treatment of Drug-Resistant Bacterial Infections
https://pubmed.ncbi.nlm.nih.gov/40315159/
jeanfrancoismaison
May 31 min read
Next-generation rifamycins for the treatment of mycobacterial infections
https://pubmed.ncbi.nlm.nih.gov/40310456/
jeanfrancoismaison
May 21 min read
Ucenprubart is an agonistic antibody to CD200R with the potential to treat inflammatory skin disease: preclinical development and a phase 1 clinical study
https://pubmed.ncbi.nlm.nih.gov/40312358/
jeanfrancoismaison
May 21 min read
HESI GTTC Ring Trial: Concordance between Ames and Rodent Carcinogenicity Outcomes for N-Nitrosamines (NAs) with Rat and Hamster Metabolic Conditions
https://pubmed.ncbi.nlm.nih.gov/40311791/
jeanfrancoismaison
May 21 min read
Immunogenicity, Reactogenicity, and Safety of a Pentavalent Meningococcal ABCWY Vaccine in Adolescents and Young Adults Who Had Previously Received a Meningococcal ACWY Vaccine: A Phase 3, Randomized
https://pubmed.ncbi.nlm.nih.gov/39722560/
jeanfrancoismaison
May 21 min read
Parenteral vaccination with recombinant EtpA glycoprotein impairs enterotoxigenic E. coli colonization
https://pubmed.ncbi.nlm.nih.gov/40310293/
jeanfrancoismaison
May 21 min read
PILRα on tumor cells interacts with the T cell surface protein CD99 to suppress antitumor immunity
https://pubmed.ncbi.nlm.nih.gov/40312493/
jeanfrancoismaison
May 21 min read
Mucosal and Systemic Antibody Responses After Boosting With a Bivalent Messenger RNA Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
https://pubmed.ncbi.nlm.nih.gov/40298376/
jeanfrancoismaison
May 11 min read
The intricate interplay among microbiota, mucosal immunity, and viral infection in the respiratory tract
https://pubmed.ncbi.nlm.nih.gov/40301955/
jeanfrancoismaison
May 11 min read
The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models
https://pubmed.ncbi.nlm.nih.gov/40298430/
jeanfrancoismaison
May 11 min read
The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances
https://pubmed.ncbi.nlm.nih.gov/40299429/
jeanfrancoismaison
May 11 min read
Comparison of human macrophages derived from peripheral blood and bone marrow
https://pubmed.ncbi.nlm.nih.gov/40073092/
jeanfrancoismaison
May 11 min read
Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice
https://pubmed.ncbi.nlm.nih.gov/40305570/
jeanfrancoismaison
May 11 min read
Immunogenicity and duration of antibodies after vaccination with a two-dose series of the nine-valent human papillomavirus vaccine among Alaska Native children: a prospective cohort study
https://pubmed.ncbi.nlm.nih.gov/40307681/
jeanfrancoismaison
May 11 min read
Cellular immune changes during severe antisense oligonucleotide-associated thrombocytopenia in a nonhuman primate model
https://pubmed.ncbi.nlm.nih.gov/40101742/
jeanfrancoismaison
May 11 min read
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