Biologics R&D: select news

CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression

https://pubmed.ncbi.nlm.nih.gov/40306957/

jeanfrancoismaison

May 11 min read

Cell-Based Assays Using Derived Human-Induced Pluripotent Cells in Drug Discovery and Development

https://pubmed.ncbi.nlm.nih.gov/40307631/

jeanfrancoismaison

May 11 min read

Cancer mRNA vaccines: clinical application progress and challenges

https://pubmed.ncbi.nlm.nih.gov/40306545/

jeanfrancoismaison

May 11 min read

Linking microbial communities to rheumatoid arthritis: focus on gut, oral microbiome and their extracellular vesicles

https://pubmed.ncbi.nlm.nih.gov/40308573/

jeanfrancoismaison

May 11 min read

Protection against N. gonorrhoeae induced by OMV-based meningococcal vaccines are associated with cross-species directed humoral and cellular immune responses

https://pubmed.ncbi.nlm.nih.gov/40292302/

jeanfrancoismaison

Apr 291 min read

Immunogenicity and safety of different immunisation schedules of the VLA15 Lyme borreliosis vaccine candidate in adults, adolescents, and children: a randomised, observer-blind, placebo-controlled, ph

https://pubmed.ncbi.nlm.nih.gov/40294611/

jeanfrancoismaison

Apr 291 min read

CAR T or NK cells targeting mismatched HLA-DR molecules in acute myeloid leukemia after allogeneic hematopoietic stem cell transplant

https://pubmed.ncbi.nlm.nih.gov/40128569/

jeanfrancoismaison

Apr 291 min read

HER3: Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway

https://pubmed.ncbi.nlm.nih.gov/40290122/

jeanfrancoismaison

Apr 291 min read

Syrian hamsters (Mesocricetus auratus) as an upper respiratory tract model for respiratory syncytial virus infection

https://pubmed.ncbi.nlm.nih.gov/40295717/

jeanfrancoismaison

Apr 291 min read

Human challenge models for vaccine development-strengths, limitations, and expansion into endemic settings: a HIC-Vac meeting report

https://pubmed.ncbi.nlm.nih.gov/40265077/

jeanfrancoismaison

Apr 281 min read

mRNA vaccines: miRNA-based controlled biodistribution and directed adjuvantation

https://pubmed.ncbi.nlm.nih.gov/40268657/

jeanfrancoismaison

Apr 281 min read

Vaccination in pregnancy to protect the newborn

https://pubmed.ncbi.nlm.nih.gov/40269273/

jeanfrancoismaison

Apr 281 min read

Role of artificial intelligence in advancing immunology

https://pubmed.ncbi.nlm.nih.gov/40272607/

jeanfrancoismaison

Apr 281 min read

Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US

https://pubmed.ncbi.nlm.nih.gov/40272967/

jeanfrancoismaison

Apr 281 min read

Resolution of historically discordant Ames test negative/rodent carcinogenicity positive N-nitrosamines using a sensitive, OECD-aligned design

https://pubmed.ncbi.nlm.nih.gov/39485309/

jeanfrancoismaison

Apr 281 min read

Neuropilin-1: A Multifaceted Target for Cancer Therapy

https://pubmed.ncbi.nlm.nih.gov/40277760/

jeanfrancoismaison

Apr 281 min read

Shared clinical and immunologic features of mRNA vaccines: preliminary results from a comparative clinical study

https://pubmed.ncbi.nlm.nih.gov/40276503/

jeanfrancoismaison

Apr 281 min read

Host immune response to respiratory syncytial virus infection and its contribution to protection and susceptibility in adults: a systematic literature review

https://pubmed.ncbi.nlm.nih.gov/40278893/

jeanfrancoismaison

Apr 281 min read

Safety of RTS,S/AS01E malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): a phase 4 cohort event monitoring study

https://pubmed.ncbi.nlm.nih.gov/40288377/

jeanfrancoismaison

Apr 281 min read

In vitro to in vivo extrapolation modeling to facilitate the integration of transcriptomics data into genotoxicity assessment

https://pubmed.ncbi.nlm.nih.gov/40288562/

jeanfrancoismaison

Apr 281 min read