Biologics R&D: select news

Developmental and Reproductive Toxicity Testing Strategies for Oligonucleotides: A Workshop Proceedings

https://pubmed.ncbi.nlm.nih.gov/40445609/

jeanfrancoismaison

May 311 min read

Quadrivalent meningococcal tetanus toxoid-conjugate booster vaccination in children aged 10-12 years: phase III randomized trial complementary analysis of immune persistence 3-6 years after priming

https://pubmed.ncbi.nlm.nih.gov/39672823/

jeanfrancoismaison

May 301 min read

Efficacy, safety, and immunogenicity of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein vaccine (RSVPreF3 OA) in older adults over three respiratory syncytial virus seasons (AReSV

https://pubmed.ncbi.nlm.nih.gov/40245915/

jeanfrancoismaison

May 301 min read

Multi-criteria decision making and its application to in silico discovery of vaccine candidates for Toxoplasma gondii

https://pubmed.ncbi.nlm.nih.gov/40378548/

jeanfrancoismaison

May 301 min read

Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials

https://pubmed.ncbi.nlm.nih.gov/40378861/

jeanfrancoismaison

May 301 min read

Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines

https://pubmed.ncbi.nlm.nih.gov/40438096/

jeanfrancoismaison

May 301 min read

Biologic drug development for treatment and prevention of sexually transmitted infections

https://pubmed.ncbi.nlm.nih.gov/40439402/

jeanfrancoismaison

May 301 min read

The effect of outcome choice on vaccine dose allocation: a modelling study

https://pubmed.ncbi.nlm.nih.gov/40441375/

jeanfrancoismaison

May 301 min read

Safety, pharmacokinetics, and neutralisation activity of PGDM1400LS, a V2 specific HIV-1 broadly neutralising antibody, infused intravenously or subcutaneously in people without HIV-1 in the USA (HVTN

https://pubmed.ncbi.nlm.nih.gov/40441807/

jeanfrancoismaison

May 301 min read

Development of bivalent RBD adapted COVID-19 vaccines for broad sarbecovirus immunity

https://pubmed.ncbi.nlm.nih.gov/40442110/

jeanfrancoismaison

May 301 min read

Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG

https://pubmed.ncbi.nlm.nih.gov/40442144/

jeanfrancoismaison

May 301 min read

Cryo-EM structures of HCV E2 glycoprotein bound to neutralizing and non-neutralizing antibodies determined using bivalent Fabs as fiducial markers

https://pubmed.ncbi.nlm.nih.gov/40442315/

jeanfrancoismaison

May 301 min read

T cell receptor mimic CAR T cells targeting cathepsin G signal peptide

https://pubmed.ncbi.nlm.nih.gov/40437170/

jeanfrancoismaison

May 291 min read

Nucleic acid vaccines: innovations, efficacy, and applications in at-risk populations

https://pubmed.ncbi.nlm.nih.gov/40438110/

jeanfrancoismaison

May 291 min read

An Industry Perspective on the Use of Novel Excipients in Lipid Nanoparticles-Nonclinical Considerations

https://pubmed.ncbi.nlm.nih.gov/40040255/

jeanfrancoismaison

May 291 min read

Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice

https://pubmed.ncbi.nlm.nih.gov/40320111/

jeanfrancoismaison

May 291 min read

How likely is it that a virus or bacteria is causing a patient's symptoms? A new approach to interpret the outcome from multi-pathogen PCR

https://pubmed.ncbi.nlm.nih.gov/39864052/

jeanfrancoismaison

May 291 min read

What is the current evidence base for measles vaccination earlier than 9 months of age?: Report from an informal technical consultation of the World Health Organization

https://pubmed.ncbi.nlm.nih.gov/40373694/

jeanfrancoismaison

May 291 min read

Hydrophobic residue substitutions enhance the stability and in vivo immunogenicity of respiratory syncytial virus fusion protein

https://pubmed.ncbi.nlm.nih.gov/40434102/

jeanfrancoismaison

May 291 min read

Evaluating the Test-Negative Design for COVID-19 Vaccine Effectiveness Using Randomized Trial Data: A Secondary Cross-Protocol Analysis of 5 Randomized Clinical Trials

https://pubmed.ncbi.nlm.nih.gov/40434773/

jeanfrancoismaison

May 291 min read