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Biologics R&D: select news
HaloPROTAC3 does not trigger the degradation of the halotagged parasitophorous vacuole membrane protein UIS4 during Plasmodium liver stage development
https://pubmed.ncbi.nlm.nih.gov/40419780/
jeanfrancoismaison
May 271 min read
Respiratory syncytial virus: health burden, disease prevention, and treatment-recent progress and lessons learned
https://pubmed.ncbi.nlm.nih.gov/40420998/
jeanfrancoismaison
May 271 min read
The validity of test-negative design for assessment of typhoid conjugate vaccine protection: comparison of estimates by different study designs using data from a cluster-randomised controlled trial
https://pubmed.ncbi.nlm.nih.gov/40252689/
jeanfrancoismaison
May 261 min read
Safety of RTS,S/AS01E malaria vaccine up to 1 year after the third dose in Ghana, Kenya, and Malawi (EPI-MAL-003): a phase 4 cohort event monitoring study
https://pubmed.ncbi.nlm.nih.gov/40288377/
jeanfrancoismaison
May 261 min read
Underlying health biases in previously-infected SARS-CoV-2 vaccination recipients: A cohort study
https://pubmed.ncbi.nlm.nih.gov/40315999/
jeanfrancoismaison
May 261 min read
COVID-19 pandemic: A multidimensional analysis and the strategic role played by developing countries vaccine manufacturers
https://pubmed.ncbi.nlm.nih.gov/40412330/
jeanfrancoismaison
May 261 min read
Challenges in coverage of future hepatitis C vaccines: Review and potential solutions
https://pubmed.ncbi.nlm.nih.gov/40412331/
jeanfrancoismaison
May 261 min read
Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody
https://pubmed.ncbi.nlm.nih.gov/40412376/
jeanfrancoismaison
May 261 min read
Vaccines in Melanoma: Past, Present, and Future
https://pubmed.ncbi.nlm.nih.gov/40413007/
jeanfrancoismaison
May 261 min read
Impact of unequal testing on vaccine effectiveness estimates across two study designs: a simulation study
https://pubmed.ncbi.nlm.nih.gov/40413178/
jeanfrancoismaison
May 261 min read
Adjunctive beneficial effect of c-di-GMP, a STING agonist, in enhancing protective efficacy of TLR4-adjuvanted tuberculosis subunit vaccine formulations
https://pubmed.ncbi.nlm.nih.gov/40414893/
jeanfrancoismaison
May 261 min read
The path to prevention of multiple sclerosis: Considerations for Epstein-Barr virus vaccine-based prevention studies
https://pubmed.ncbi.nlm.nih.gov/40415641/
jeanfrancoismaison
May 261 min read
How useful are 3-month repeat-dose toxicology studies for the development of T cell engagers for oncology indications?
https://pubmed.ncbi.nlm.nih.gov/40414274/
jeanfrancoismaison
May 261 min read
The guinea pig as a relevant preclinical model in the rat race for a vaccine against congenital cytomegalovirus infection
https://pubmed.ncbi.nlm.nih.gov/40413831/
jeanfrancoismaison
May 261 min read
Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high grade glioma models
https://pubmed.ncbi.nlm.nih.gov/40411488/
jeanfrancoismaison
May 251 min read
Framework for classifying chemicals for repeat dose toxicity using NAMs
https://pubmed.ncbi.nlm.nih.gov/40411533/
jeanfrancoismaison
May 251 min read
Maternal Vaccination and Protective Immunity Against SARS-CoV-2 Infection in Pups
https://pubmed.ncbi.nlm.nih.gov/40411252/
jeanfrancoismaison
May 251 min read
Preclinical development of siRNA conjugates to target tumor antigens
https://pubmed.ncbi.nlm.nih.gov/40407051/
jeanfrancoismaison
May 241 min read
Discovery of AB801, a Potent and Selective Inhibitor of AXL Receptor Tyrosine Kinase for Use in Cancer Therapy
https://pubmed.ncbi.nlm.nih.gov/40407274/
jeanfrancoismaison
May 241 min read
An antibody-drug conjugate targeting soluble and membrane-bound TGFα is effective against pancreatic tumors
https://pubmed.ncbi.nlm.nih.gov/40410803/
jeanfrancoismaison
May 241 min read
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