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Biologics R&D: select news
Toxoplasma gondii C2 Domain Protein Deletion Mutant as a Promising Vaccine Against Toxoplasmosis in Mice
https://pubmed.ncbi.nlm.nih.gov/40407413/
jeanfrancoismaison
May 241 min read
Generative Deep Learning Design of Single-Domain Antibodies Against Venezuelan Equine Encephalitis Virus
https://pubmed.ncbi.nlm.nih.gov/40407693/
jeanfrancoismaison
May 241 min read
Development of Langat virus infectious clones as a platform for live-attenuated tick-borne encephalitis vaccine
https://pubmed.ncbi.nlm.nih.gov/40410304/
jeanfrancoismaison
May 241 min read
Evaluation of broad-spectrum protection by novel mRNA vaccines against SARS-CoV-2 variants (Delta, Omicron-BA.5, XBB-EG.5) in the golden hamster model
https://pubmed.ncbi.nlm.nih.gov/40410742/
jeanfrancoismaison
May 241 min read
IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell-mediated cytotoxicity of PD-L1 positive tumor cells
https://pubmed.ncbi.nlm.nih.gov/40402523/
jeanfrancoismaison
May 231 min read
Development of a Novel Engineered Antibody Format for PSMA-Targeted Radionuclide Therapy
https://pubmed.ncbi.nlm.nih.gov/40403225/
jeanfrancoismaison
May 231 min read
Intracerebroventricular phospho-tau immunotherapy alleviates cortical phospho-tau burden and motor phenotype in a neuron-specific P301S tauopathy mouse
https://pubmed.ncbi.nlm.nih.gov/40403829/
jeanfrancoismaison
May 231 min read
INBRX-106: a hexavalent OX40 agonist that drives superior antitumor responses via optimized receptor clustering
https://pubmed.ncbi.nlm.nih.gov/40404202/
jeanfrancoismaison
May 231 min read
Insights from the bottom-up development of LGR5-targeting immunotherapeutics
https://pubmed.ncbi.nlm.nih.gov/40405910/
jeanfrancoismaison
May 231 min read
Evaluation of capsule polysaccharide (CPS)-specific antibodies for broad recognition of prominent multidrug-resistant Klebsiella pneumoniae
https://pubmed.ncbi.nlm.nih.gov/40401961/
jeanfrancoismaison
May 231 min read
Cross-reactive sarbecovirus antibodies induced by mosaic RBD nanoparticles
https://pubmed.ncbi.nlm.nih.gov/40402246/
jeanfrancoismaison
May 231 min read
Molecular mimicry between parasites and cancer: a novel approach for developing cancer vaccines and therapeutic antibodies
https://pubmed.ncbi.nlm.nih.gov/40402283/
jeanfrancoismaison
May 231 min read
Comparative duration of neutralizing responses and protections of COVID-19 vaccination and correlates of protection
https://pubmed.ncbi.nlm.nih.gov/40404724/
jeanfrancoismaison
May 231 min read
SLAMF6 regulates basal T cell receptor signaling and influences invariant natural killer T cell lineage diversity
https://pubmed.ncbi.nlm.nih.gov/40405353/
jeanfrancoismaison
May 231 min read
Artificial intelligence in vaccine research and development: an umbrella review
https://pubmed.ncbi.nlm.nih.gov/40406131/
jeanfrancoismaison
May 231 min read
Live attenuated SARS-CoV-2 vaccine OTS-228 demonstrates efficacy, safety, and stability in preclinical model
https://pubmed.ncbi.nlm.nih.gov/40404620/
jeanfrancoismaison
May 231 min read
TnSeq identifies genetic requirements of Mycobacterium tuberculosis for survival under vaccine-induced immunity
https://pubmed.ncbi.nlm.nih.gov/40404665/
jeanfrancoismaison
May 231 min read
Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology
https://pubmed.ncbi.nlm.nih.gov/40406115/
jeanfrancoismaison
May 231 min read
Zelenectide pevedotin (BT-8009): a bicyclic peptide toxin conjugate targeting nectin-4 for the treatment of bladder cancer
https://pubmed.ncbi.nlm.nih.gov/40401457/
jeanfrancoismaison
May 221 min read
Considerations for Use of Humanized IgG1/4 Göttingen Minipigs in Safety Assessment of Antibody-Based Therapeutics
https://pubmed.ncbi.nlm.nih.gov/40398719/
jeanfrancoismaison
May 221 min read
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