Biologics R&D: select news

Tumor microenvironment noise-induced polarization: the main challenge in macrophages' immunotherapy for cancer

https://pubmed.ncbi.nlm.nih.gov/39827422/

jeanfrancoismaison

May 221 min read

mRNA-based seasonal influenza and SARS-CoV-2 multicomponent vaccine in healthy adults: a phase 1/2 trial

https://pubmed.ncbi.nlm.nih.gov/40102593/

jeanfrancoismaison

May 221 min read

Cemiplimab plus peltopepimut-S vaccine in recurrent cervical cancer: A phase 2 clinical trial

https://pubmed.ncbi.nlm.nih.gov/40154184/

jeanfrancoismaison

May 221 min read

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

https://pubmed.ncbi.nlm.nih.gov/40240603/

jeanfrancoismaison

May 221 min read

Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes

https://pubmed.ncbi.nlm.nih.gov/40354414/

jeanfrancoismaison

May 221 min read

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules

https://pubmed.ncbi.nlm.nih.gov/40396589/

jeanfrancoismaison

May 221 min read

Human genetics of responses to vaccines

https://pubmed.ncbi.nlm.nih.gov/40397507/

jeanfrancoismaison

May 221 min read

Human monoclonal antibodies targeting subdominant meningococcal antigens confer cross-protection against gonococcus

https://pubmed.ncbi.nlm.nih.gov/40397716/

jeanfrancoismaison

May 221 min read

Guided design for the development of an evolution-proof influenza vaccine

https://pubmed.ncbi.nlm.nih.gov/40398325/

jeanfrancoismaison

May 221 min read

Reflections on 50 years of immunisation programmes in the WHO African region: an impetus to build on the progress and address the unfinished immunisation business

https://pubmed.ncbi.nlm.nih.gov/40398892/

jeanfrancoismaison

May 221 min read

Mpox multiprotein virus-like nanoparticle vaccine induces neutralizing and protective antibodies in mice and non-human primates

https://pubmed.ncbi.nlm.nih.gov/40399314/

jeanfrancoismaison

May 221 min read

Transcriptomic analysis of DENV-2-infected human dermal fibroblasts identified potential mechanisms that suppressed ZIKV replication during sequential coinfection

https://pubmed.ncbi.nlm.nih.gov/40399994/

jeanfrancoismaison

May 221 min read

Optimizing HPV vaccine effectiveness: impact of vaccination age and dose schedule on immunogenicity and cervical cancer prevention

https://pubmed.ncbi.nlm.nih.gov/40401053/

jeanfrancoismaison

May 221 min read

Robust Multiepitope Vaccine from Glycoproteins Against Human Metapneumovirus Genotypes A2a, A2b, and A2c by Utilizing Immunoinformatics and Reverse Vaccinology Approaches

https://pubmed.ncbi.nlm.nih.gov/40401430/

jeanfrancoismaison

May 221 min read

Minimizing batch-to-batch variability of a live virus vaccine by process analytical technologies

https://pubmed.ncbi.nlm.nih.gov/40401434/

jeanfrancoismaison

May 221 min read

Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy

https://pubmed.ncbi.nlm.nih.gov/40398537/

jeanfrancoismaison

May 221 min read

Drug delivery strategies to cross the blood-brain barrier in Alzheimer's disease: a comprehensive review on three promising strategies

https://pubmed.ncbi.nlm.nih.gov/40393907/

jeanfrancoismaison

May 211 min read

Adenosine Kinase: An Epigenetic Modulator and Drug Target

https://pubmed.ncbi.nlm.nih.gov/40393929/

jeanfrancoismaison

May 211 min read

United States Environmental Protection Agency's Perfluorooctanoic Acid, Perfluorooctane Sulfonic Acid, and Related Per- and Polyfluoroalkyl Substances 2024 Drinking Water Maximum Contaminant Level: Pa

https://pubmed.ncbi.nlm.nih.gov/40391660/

jeanfrancoismaison

May 211 min read

Lnc-DARVR/miR-365-1-5p/LAMB1 axis regulates rotavirus replication via the complement C3 pathway

https://pubmed.ncbi.nlm.nih.gov/40237496/

jeanfrancoismaison

May 211 min read